Octodon degus (Molina 1782): A Model in Comparative Biology and Biomedicine
نویسندگان
چکیده
منابع مشابه
Recollection of What-where-which Memory in Degus (octodon Degus)
To examine if a feature of episodic-like memory reported in rats is shared with other species, we investigated whether degus would form an integrated memory of object (what), place (where), and context (which). We used two E-shaped mazes with different contexts regarding the wall and the floor. Degus were entered into the middle arm and first explored the maze with two trial-unique objects plac...
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Alzheimer's disease primarily occurs as sporadic disease and is accompanied with vast socio-economic problems. The mandatory basic research relies on robust and reliable disease models to overcome increasing incidence and emerging social challenges. Rodent models are most efficient, versatile, and predominantly used in research. However, only highly artificial and mostly genetically modified mo...
متن کاملWheel-running and rest activity pattern interaction in two octodontids (Octodon degus, Octodon bridgesi).
Wheel-running and other non-photic stimuli influence the rest-activity pattern of diurnal and nocturnal mammals. A day to night inversion of phase preference of activity was described among Octodon degus, when exposed to ad-libitum wheel running. We have studied the rest-activity pattern response in presence of ad libitum wheel-running in wild-captured male individuals from two species of genus...
متن کاملTítulo Artículo / Títol Article: Octodon Degus: a Model for the Cognitive Impairment Associated with Alzheimer's Disease Octodon Degus: a Model for the Cognitive Impairment Associated with Alzheimer's Disease
Octodon degus (O. degus) is a diurnal rodent that spontaneously develops several physiopathological conditions, analogous in many cases to those experienced by humans. In light of this, O. degus has recently been identified as a very valuable animal model for research in several medical fields, especially those concerned with neurodegenerative diseases in which risk is associated with ageing. O...
متن کاملOctodon Degus: A Strong Attractor for Alzheimer Research
The most popular animal models of Alzheimer’s disease (AD) are transgenic mice expressing human genes with known mutations which do not represent the most abundant sporadic form of the disease. An increasing number of genetic, vascular and psychosocial data strongly support that the Octodon degus, a moderate-sized and diurnal precocial rodent, provides a naturalistic model for the study of the ...
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ژورنال
عنوان ژورنال: Cold Spring Harbor Protocols
سال: 2013
ISSN: 1559-6095
DOI: 10.1101/pdb.emo071357